Irish Independent Park will host the clash as two of the province’s oldest clubs face off in a repeat of last season’s final.
It could be history in the making for the Temple Hill outfit as they seek their second ever three-in-a-row, last achieved by the club almost 100 years ago.
Garryowen are the competition’s most successful side and will be looking to add to their hugely impressive haul of 38 Munster Senior Challenge Cup titles.
Cork Con progressed to the final thanks to home wins over Sunday’s Well, Bruff and Young Munster.
Garryowen, meanwhile, navigated their way past Tipperary sides Nenagh Ormond and Cashel before their convincing semi-final win over UL Bohemian.
Munster Senior Challenge Cup Final
Saturday, January 24: Cork Constitution v Garryowen, Irish Independent Park, KO 4pm